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Its anti-neoplastic effects are related to the pro-angiogenic factors and growth inhibition, induction of endothelial cells apoptosis through a p53-dependent pathway involving Bcl-2/Bax, cytochrome C release, Apaf-1, and activation of caspase-3 and PARP (3,14)

Analysis of omics data usually involves multivariate statistical analyses such as principal component analysis (PCA), partial least squares discriminant analysis (PLS-DA) and other bioinformatics statistical methods (Kettaneh et al

13, 14 The GFAP is considered a very important stress marker in diverse retinal pathologies and in experimental models of ocular hypertension

Active malignancy warrants avoidance as discussed above

This so-called ETosis is often associated with cell death of the producing MC, and the type of stimulus potentially determines the ratio of surviving vs