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No, la semaglutida no debe sustituir a las estatinas cuando estas estn indicadas

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Concomitant diseases of patients in this trial included, but were not limited to, heart failure (24%), hypertension (93%), history of ischemic stroke (12%) and history of a myocardial infarction (33%)

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Reconstitution volume does not directly reduce peptide potency, but larger water volumes (35mL per 1mg vial) can marginally accelerate oxidative degradation over the 28-day refrigerated shelf life compared to 12mL volumes