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HBE cells were plated at a density of 1 10 4 per well in a 96-well plate and treated with 0, 12.5, 25, 50, 100, 250, 500, 1 000 g/ml (corresponding to 0, 3.91, 7.81, 15.62, 31.25, 78.13, 156.25, 312.5 g/cm 2 ) Al 2 O 3 NPs with eight biological replicates for each concentration

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This dysfunction extends beyond digestion