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Dapagliflozin 10 mg was evaluated in two glycemic control trials that included adult patients with moderate renal impairment (an eGFR of 45 to less than 60 mL/min/1.73 m, and an eGFR of 30 to less than 60 mL/min/1.73 m) [see Clinical Studies ]

Access to GLP-1s is only available to people with a BMI of 30 or higher, or 27 and higher with a weight-related health condition like high blood pressure, high cholesterol, or type 2 diabetes

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GLP-1 medications like semaglutide have a 7-day half-life, meaning trace amounts remain in your system for 3 to 4 weeks

-10.9% lean body mass over 72 weeks) per the SURMOUNT-1 body-composition substudy [12]