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The single human dataset for musculoskeletal use is a retrospective chart review of sixteen knee-pain patients who paid for intra-articular injections, with subjective improvement reported in fourteen and no control, no blinded assessment, and no objective imaging endpoint
The cold sensitivity on GLP-1 compounds is another commonly reported experience that resolves as the body adapts to new weight and metabolic patterns
Gastrointestinal effects are the most common and include nausea, vomiting, diarrhea, and constipation
The FDA has identified concerns with compounded BPC-157, including possible immunogenicity risks, peptide-related impurities, and limited safety information for proposed routes of administration
The F-actin formation as detected by FITC-phalloidin staining was induced in BPC 157-treated fibroblasts