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Semaglutide, either alone or combined with papaya, effectively modulated these apoptotic markers by downregulating Bax and caspase-3 while upregulating Bcl-2

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These adipokines facilitate processes such as tumor epithelial-mesenchymal transition (EMT), suppress the immune system, and counteract apoptosis, all of which contribute to cancer progression (Saha et al., 2023)