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ADHD: Histamine-related variants increase the risk of ADHD Early morning waking / insomnia: One underlying cause of early morning insomnia is that high histamine levels cause too much alertness

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We and others showed that administration of LAC leads to a rapid regulation of plasticity of brain areas such as the hippocampus and the connected prefrontal cortex, which are implicated in MDD and are among the first brain structures to degenerate in Alzheimers Disease (AD) [26, 30, 34,35,36, 45]

10.1016/0140-6736(91)92978-b 33 CrellinD.LingR

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