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Gastrointestinal Adverse Events Gastrointestinal (GI) adverse events are the hallmark safety finding with all GLP-1 receptor agonists, reflecting the physiological effects of GLP-1 signaling on gastric motility, gastric emptying, and central appetite regulation
Lower Heart Risk: Semaglutide has been shown to reduce the risk of heart attack, stroke, and cardiovascular death in those with type 2 diabetes
Zepbound (tirzepatide) : Up to 22.5% body weight loss , the best results yet
The SUSTAIN-6 trial, a landmark study, revealed that semaglutide significantly reduced the risk of major adverse cardiovascular events, including heart attack, stroke, and cardiovascular death, compared to placebo
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