Using the Connectivity Map, a software gene profiling tool developed by the Broad Institute, the researchers sorted through gene expression profiles of biological molecules and came up with GHK as a compound which could reverse changes in gene expression associated with emphysematous destruction, such as decreased activity of genes involved in the TGF- pathway
In the research context the molecule also appears in combination protocols for tendons and joints together with BPC-157 and TB-500
Fabrini R, De Luca A, Stella L, Mei G, Orioni B, Ciccone S et al
(2003), which tested BPC-157 on transected rat Achilles tendons
Soares PIP, Alves AMR, Pereira LCJ, Coutinho JT, Ferreira IMM, Novo CMM, Borges J (2014) Effects of surfactants on the magnetic properties of iron oxide colloids
Elkoshi Z (2021) The binary classification of protein kinases