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Without Medicaid, approximately half of adults with opioid use disorder who recognize treatment need report cost or lack of insurance as primary barriers

[3] FDA

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Nausea incidence is similar, affecting 25-35% of users on both drugs

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People who have gastrointestinal disorders like celiac disease or Crohn's disease or who have undergone weight-loss surgery may secrete too little hydrochloric acid or intrinsic factor