GSLs, the precursors of ITCs, constitute in addition to their role in defence responses a storage for reduced sulfur as well as a good example on how the partitioning of this macronutrient is controlled between primary and secondary metabolism 82
This correlates with an increased GST activity in the tissue, which translates in a reduced CSF level of 1-chloro-2,4-dinitrobenzene (CDNB), a prototypic GST substrate used to evaluate in vivo the efficiency of the GSH-dependent enzymatic blood-CSF barrier
ACSL4 plays a dual role in MM: it promotes tumor growth by activating lipid synthesis, but also initiates ferroptosis by catalyzing the production of PUFA-CoA, a key substrate for lipid peroxidation (Zhang et al., 2023)
He said naturally occurring peptides were kept within very particular levels by the body, meaning that increasing their levels via injections could throw its systems out of balance
Kanski, J., Hong, S
Atrial Natriuretic Peptide Induces Postprandial Lipid Oxidation in Humans
