We did not examine posttranslational modifications linked to target degradation such as ubiquitination, but note that the GLP-1R is not ubiquitinated by treatment with exendin-4 (Jones et al., 2018a)
The question now is how to demonstrate it experimentally
Ozempic have many of the same side effects, but you have to watch out for low blood sugar if you are not careful
What is the functional significance of the unique location of glutaredoxin 1 (GRx1) in the intermembrane space of mitochondria
Published research has documented glutathiones central role in neutralizing free radicals, supporting hepatic detoxification pathways, regenerating other antioxidants like vitamin C and vitamin E, and modulating inflammatory cascades
$^1$ : p-5 Nuclear quantum effects are particularly important in the different properties of light (H2O) and heavy water (D2O) where the more restricted atomic vibrations in D2O reduce the negative effect of its van der Waals repulsive core so increasing its overall hydrogen bond energy
