Common side effects include nausea, vomiting, diarrhoea, and abdominal discomfort, particularly during treatment initiation
May decrease visceral fat
Large-scale clinical trials of tirzepatide show that itching and pruritus occur infrequentlygenerally affecting less than 5% of treatment participants in most studies
The group with type 2 diabetes plus a second-line diabetes medication prescription (dipeptidyl peptidase-4 inhibitors [DPP-4i], sodium glucose cotransporter 2 inhibitors [SGLT2i] and sulfonylureas) was made up of 1,614,495 adults (mean age, 63.7 years
Non-prescription drugs like ibuprofen and acetaminophen, as well as dietary supplements such as fish oil, calcium, and iron, should be considered for potential interactions
Pandey S, Mangmool S, Parichatikanond W