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Full-length growth hormone affects blood sugar regulation, stimulates IGF-1 production, causes fluid retention, and can lead to joint pain and carpal tunnel syndrome

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Because of this and the fact that the body only needs a small amount of vitamin B12 each day, it can take up to a year or even longer for an inadequate vitamin B12 to manifest as an apparent deficiency

SURMOUNT-5 added another critical data point by directly comparing tirzepatide to semaglutide, which was previously considered the gold standard among GLP-1 agonists

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