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Comparing the two requires stitching together separate trials that differ in sponsor, population, duration, and comparator a chain with several weak links

Netea et al., 2020

Enhanced Keap1-Nrf2 signaling protects the myocardium from isoproterenol-induced pathological remodeling in mice

Sterile water is also the appropriate choice in clinical settings where single-use protocols are required by policy

PMID 18397973

The authors also hypothesize that the structural symmetry of Rb1, with disaccharide units on each side of the gonane nucleus, contributes to its stronger anti-aggregate properties compared to Rg3, which has only a single disaccharide group attached to C-3 of the triterpene (Oliveri et al