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Managing insulin resistance, PCOS, or a history of restrictive eating

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A recent review of GLP-1 studies found that patients got healthier hearts and blood sugar, but saw no improvement in cardiorespiratory fitness (VO max), likely because of muscle loss despite better weight and heart metrics

Another angle explored by researchers involves semaglutides potential to improve insulin sensitivity

Liquid calories from sugary drinks, alcohol, or high-calorie coffee beverages are particularly problematic because they don't trigger the same satiety signals as solid foods

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