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A research sought to evaluate the in vivo Anticancer effectiveness of Cantide, both as a standalone treatment And in conjunction with 5-fluorouracil, utilizing an orthotopic human HCC mice model

Phase 2 (Weeks 5 through 8): 0.50mg per week The first therapeutic dose level

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Diabetes, obesity & metabolism, 26 Suppl 4, 1627

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Inspired by rat amylin, which is less prone to dimerize, the enhanced stability of pramlintide compared to human amylin was achieved by introducing three amino acid substitutions (pro25,28,29) into the sequence of human amylin ( Table 1 )