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A fast ADH or a slow ALDH are expected to elevate acetaldehyde levels and thus reduce alcohol drinking

Under such conditions, the body will experience oxidative stress

Finally, after an additional 4 weeks, the dose should be increased to the maintenance dose of 2.4 mg per week

iScience 25 , 105141 (2022)

2,2426 Overall, polyethylene glycol achieves equal or better treatment success than other laxatives, such as lactulose or milk of magnesia, 30,33,34 although it may be associated with more episodes of fecal incontinence