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This article thoroughly traces the developmental milestones of GLP-1 drugs, from their initial discovery to their clinical application, detailing the evolution of diverse GLP-1 medications along with their distinct pharmacological properties

Potential theoretical concerns include: Unregulated angiogenesis Immune system modulation Tumor growth acceleration under certain conditions Reproductive safety implications Cardiovascular remodeling There is no clinical evidence demonstrating these risks in humans, but comprehensive trials evaluating these endpoints do not exist

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S., Mani, H., Banaudha, K., Maheshwari, R