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Extracellular matrix remodeling: GHK-Cu modulates the expression of over 4,000 genes, many of which are involved in tissue remodeling, stress response, and apoptosis

[186] induced AS in ApoE-deficient mice using a high-fat diet and treated them with a ferroptosis inhibitor ferrostatin-1 (Fer-1)

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3) Growth-Hormone Receptor (GHR) Up-regulation & JAK2 Signaling (Tendon Fibroblasts) In rat tendon fibroblasts, BPC-157 up-regulated growth hormone receptor and enhanced downstream JAK2 activation upon GH exposure, correlating with proliferative markers