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Am J Physiol Endocrinol Metab 293, Pharmacol

(2511.HK), a biopharmaceutical company specialising in the development of multifunctional, multi-targeted therapies for chronic metabolic diseases, announced positive 52-week safety and efficacy results from the open-label extension (OLE) phases of two Phase III trials (SYMPHONY-1 and SYMPHONY-2) evaluating HTD1801 in patients with type 2 diabetes mellitus (T2DM)

S.NagelG.RothenbacherD.RosenbohmA.LudolphA

A number of studies reported that VDR expression can be altered under pathological conditions such as atherosclerosis, where inflammation and oxidative stress also negatively impact on vitamin D signalling [50, 51]

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