A: Contraindications include diabetes type 1, personal or family history of thyroid cancer (Medullary Thyroid Carcinoma/Multiple Endocrine Neoplasia Syndrome type 2), hypersensitivity to drug, pregnancy- caution with renal impairment, GI disease, gastroparesis, pancreatitis and diabetic retinopathy
The exact mechanism causing fatigue is not fully understood , but several factors likely contribute
Clinical Evidence: GLP-1 Medications and Cardiovascular Benefits For many people, losing weight isnt just about looking betterits about feeling better and lowering serious health risks
Summary: Glucagon-like peptide-1 receptor agonists are injectable or oral medicines that lower blood glucose in type 2 diabetes by stimulating insulin release, suppressing glucagon, slowing digestion, and reducing appetite, often leading to weight loss and cardiovascular benefits
Chen: "Theyve been used for diabetes for over a decade
Liraglutide 3.0 mg for the management of insufficient weight loss or excessive weight regain post-bariatric surgery