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To combat the endothelial dysfunction that deprives tissues of oxygen, Alpha Lipoic Acid acts directly on the vascular lining

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IGF-1 is a small polypeptide consisting of 70 amino acids that is synthesized and secreted into the bloodstream mainly by the liver and some IGF-1 is acted upon by the kidneys or skeletal muscles in an autocrine or paracrine manner in their own tissues or periphery (7)

10.1007/s12031-018-1186-z 5 Alinaghi LangariA.NezhadiA.KameshkiH.JorjafkiS

Cerebrospinal fluid concentrations of N -acetylcysteine after oral administration: phase I trial in Parkinson's disease [abstract 664]