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Take 2 capsules daily on an empty stomach, ideally 30 minutes before meals with a glass of water

The strongest human evidence is topical, including the Leyden 2002 photoaging trial and a 2023 IRB-approved 21-woman topical NEEL gel study reporting an average 28% increase in skin collagen density at 3 months

doi: 10.1016/j.jaad.2020.06.1009

Ferenci, P

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