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In addition, it plays a role in maintaining levels of blood glucose and a robust metabolism

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Furthermore, owing to the heterogeneity and diversity of tumor cells themselves, the role of IGFs is not necessarily only as a tumor suppressor, so the development of related inhibitors must fully consider the impact on the tumor and its surrounding environment

For dose justification, Semaglutide exhibited dose-dependent anti-obesity effects at doses ranging from 0.3 to 30 nmol/kg, and the maximum effective dose of 30 nmol/kg/day was selected from prior DIO mice studies [27]

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