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Both enzymes consume ATP but only the former enzyme is subject to feedback inhibition by glutathione, which competes with glutamic acid for the active site

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Gong N, Xiao Q, Zhu B, Zhang CY, Wang YC, Fan H et al (2014) Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity

Nature 488 , 665669 (2012)

Therefore, before starting any new medication, well discuss your complete medical history to ensure the medication is right for you