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Plasma can differ in the kinds and amounts of antibodies it contains

6.6 When to Refer Referral to a clinician or dietitian may be appropriate when: Persistent GI intolerance limits intake Weight loss exceeds 20% body weight Multiple laboratory abnormalities are present Underlying malabsorptive or gastrointestinal disease exists Patient is elderly or medically complex GLP-1 therapy should not occur in isolation from nutritional oversight when risk factors are present

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It was suggested that the anorectic effects were due to activation of pre-synaptic inhibitory Y2 receptors on arcuate NPY/AgRP neurons, resulting is a reduced inhibition of POMC neurons by the inhibitory neurotransmitter, -aminobutyric acid (GABA) (107)

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