GHK-Cu may prevent oxidative stress and promote healing in aged skin
10.1016/j.lfs.2022.120753 Life Sci
Lipid peroxidation is induced by hydroxyl, peroxyl, and alkoxy radicals that destroy the lipid membrane by interacting with the methylene group of fats
NQO1 metabolizing benzene, quinones, air pollution NAT1 and NAT2 N-acetyltransferases, cigarette smoke, hydrocarbons COMT adds methyl groups to modify endogenous substances, including estrogen, for elimination Elimination: Phase III Transporter Proteins Phase I and Phase II happen inside your cells, but once a metabolite has been made water-soluble, it still has to physically leave the cell and then the body
The effect on the enzyme activity appeared to be dose dependent (Figure 11A, B)
The reduced ATP level in ASA treated cells was dose dependent