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Possible effects on energy balance and body composition: Some data suggest modest improvements in energy expenditure and preferential loss of fat mass versus lean mass, but appetite suppression is the dominant driver of weight loss

doi: 10.1213/ane.0000000000006888 21

UK Clinical Guidance GLP-1 receptor agonists are medications used to manage type 2 diabetes and support weight management, traditionally given by injection

Willow , for example, ran ads encouraging patients to cancel their gym membership and promised rapid weight lossmessaging that directly contradicts clinical guidelines and feeds into unhealthy narratives (they also prescribe to patients regardless of BMI)

Berberine is among the better-researched plant compounds, especially in the context of blood sugar regulation and insulin sensitivity

However, you might be surprised to learn that the keto diet has similarly compelling benefits, according to some data