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Velusetrag improves gastroparesis both in symptoms and gastric emptying in patients with diabetic or idiopathic gastroparesis in a 12-week global phase 2B study

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a , Growth curve analysis of WT (light blue circles), gsh2 (blue squares or circles), and gsh2::GSH2 (light blue squares) strains grown in rich or minimal medium with and without methionine (Met), cysteine (Cys), or ascorbic acid (AA) supplementation at the indicated concentrations

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IGF-1 signaling can promote cell proliferation and block programmed cell death, effects that could theoretically support tumor growth if cancer cells are present