In pigs, which are considered tolerant concerning iodine excess, high iodine doses up to 10 mg/kg caused a significant downregulation of NIS in the thyroid gland and, simultaneously, it decreased mRNA expression of clue antioxidative enzymes, such as SOD and GPx, either in the liver or in the kidney or in muscles (target tissues of thyroid hormone action), however without affecting lipid peroxidation [196]
2025b) Therefore, it is now clear that free radicals are active participants in various processes and should no longer be considered merely as damaging agents, but rather as key players in many normal functions of living organisms (Gven et al
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(2023) 64:S37993
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Erratum: reduction of abeta amyloid pathology in appps1 transgenic mice in the absence of gut microbiota
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