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Neuroimaging could aid in a better understanding of the factors influencing BBB dysfunction and may lead to new ways of thinking about pathogenesis and possibly treatment and prevention of neurological disorders (Lakhan et al., 2013

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Next, GS-4997, a specific ASK1 inhibitor, was used to confirm that the expression of SREBF1 and PLIN2 is regulated by ASK1-p38/JNK signalling

Moreover, HMPSNE produced a bell-shaped effect on several cellular bioenergetic parameters related to oxidative phosphorylation, while other bioenergetic parameters were either unaffected or inhibited at the highest concentration of the inhibitor [218]

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