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It is a synthetic analog of the -melanocyte-stimulating hormone (-MSH) that is often used to promote skin tanning without exposure to harmful UV rays

In the two epilepsy models as mentioned above, the decrease of class I HDACs initiates the acetylation of histone H4 protein in rat hippocampal neurons and thereby activates the factors involved in epileptogenesis such as immediate early genes (IEGs) (e.g

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