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doi: 10.2337/dc14-1596
It may also lead to muscle weakness in people with uremia, seizures in those with seizure disorders, and could potentially affect thyroid hormone activity
Research, including the STEP 1 extension study with semaglutide, consistently shows that most people experience a return of appetite to pre-treatment levels within weeks of discontinuation
Instead, they were derived from large observational cohorts, retrospective comparative analyses, and pooled real-world datasets
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FIGURE 2 3 Clinical applications of GLP-1RAs: comprehensive protection through multi-disease risk reduction 3.1 Cardiovascular protection GLP-1RAs confer substantial cardiovascular benefits that extend beyond glycemic control, primarily by reducing the incidence of major adverse cardiovascular events (MACE)
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