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Important notice is that chelating power starts at pH 4-5 and is highest at pH 8-8.5 when citric acid is fully ionized

This context-sensitivity is characteristic of compounds that interact with upstream transcriptional regulators rather than directly with NOS enzymatic activity

29.7 mg/dL

Thus, through genetic manipulation of GSH biosynthesis, the present study, along with the BSO study, implicates a role for chronic GSH depletion in protection against ethanol-induced hepatotoxicity