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At one year, patients with PCOS on GLP-1s experienced significantly greater weight loss than those on metformin

Investigations to date have demonstrated promising safety and efficacy profiles [178]

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Accordingly, in some embodiments, cyclodextrins are included to increase the solubility of the therapeutic agents, or auris-acceptable otic agents, within the formulations or compositions described herein

Moreover, the adoption is being accelerated by favorable regulatory approvals and an increased focus on integrated cardiometabolic care