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Cleveland Clinic Thus, the benefits of surgery tend to stick, whereas the benefits of medical therapy once therapy stops or compliance wanes

If too much lean mass is lost during treatment, patients may feel weaker and may have a harder time maintaining healthy results over time

However, individual responses vary

Week 12 showed more substantial progress at 8-9% weight loss, with visible changes in body composition becoming apparent

Why it works: Hot foods release more aroma compounds

If you are starting with 80 or more pounds to shed, Retatrutides faster pace means you spend fewer months in active weight loss before reaching your target, which reduces the window during which side effects, adherence challenges, and lifestyle disruption are at their peak