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These macrophages, upon internalizing oxidized low-density lipoprotein (oxLDL), transform into foam cells, giving rise to early atherosclerotic lesions

However, as triggering the compensatory responses, blocking a single glutamine transporter is not enough to prevent tumor growth

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However, leptin replacement does not completely prevent the neuroendocrine adaptations induced by weight loss 1, 3, 5 , indicating the existence of critical additional, but still unknown, starvation signals

The modes of treatment differ with the severity of the symptoms and the response of the individual to treatment