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These results suggest that NRF2 addiction in cancer cells is established only after overcoming disadvantages and liabilities accompanying the persistent transcriptional activation mediated by NRF2

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Depending on the PAIS severity and on the individual, standard inflammatory tests such as CRP, may be completely normal or slightly elevated

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qRT-PCR was performed using SYBR Green PCR kit (Takara, China) and CFX96 Touch Real-Time PCR Detection System (Bio-Rad, USA)

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