In infected cells, all three proteins are initially inserted into the endoplasmic reticulum (ER) and are then trafficked to the ER-Golgi intermediate compartment (ERGIC) and the Golgi where they are glycosylated, and in the case of S also cleaved, by Golgi enzymes 7,8
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ACS Nano 8:19721994 Cornelio D, Roesler R, Schwartsmann G (2007) Gastrin-releasing peptide receptor as a molecular target in experimental anticancer therapy
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doi: 10.1038/nprot.2007.152
These results were observed in a specific clinical population under controlled conditions and may not generalize to other groups