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Despite consuming similar quantities of food, the mice that received milk thistle lost about 5% of their weight, while the control group continued gaining weight throughout the study ( A handful of small human studies have evaluated milk thistles effects on certain metabolic symptoms associated with obesity, such as insulin resistance and inflammation, but none have looked specifically at milk thistles ability to promote fat loss ( Although the results are promising, a single animal study does not constitute enough evidence to reliably determine whether milk thistle can aid weight loss in humans
The MOXI randomized trial did not show improved live birth or semen outcomes with one antioxidant combination, and the large SUMMER trial published in 2025 similarly found no significant improvement in ongoing pregnancy rates with the tested antioxidant supplement versus placebo
References: K
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Similarly, people with diabetes may notice reduced damage with other conditions like neuropathy, kidney function or even lung function
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