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As a result, it is estimated that 29% to 44% of adults with PWS may suffer from bone fractures due to the higher prevalence of osteoporosis, reported to be as high as 21% (78)

Gianutsos et al., 1997)

Our results indicated indeed also a higher susceptibility of glutathione mutants than WT towards SFN, which demonstrates that the phenotype induced by AITC is not unique but can be triggered by other ITCs

Furthermore, HMOX1 and PTGS2 are regulated by 13 and 20 transcription factors, respectively