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Nephrol Dial Transplant 29(Suppl 4):iv87-94

One study found that IGF-1 stimulates the proliferation of myofibroblasts in a dose-dependent manner

Senescent fibroblasts exhibit higher expressions of Bcl-2, conferring resistance to apoptosis [22]

Overcoming glutathione S-transferase P1-related cisplatin resistance in osteosarcoma

In contrast, a study of first-episode cases reported elevated glutathione in medial temporal lobes [27] raising the possibility that glutathione abnormalities might vary with phase of illness