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FDA regulatory status - compounded GLP-1s: FDA proposed April 30, 2026 to exclude semaglutide and tirzepatide from 503B Bulks List
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TRIUMPH-4 (Phase 3, 68 weeks) 12mg dose: 28.7% weight loss (~71 lbs / 32 kg average) 9mg dose: 26.4% weight loss (~64 lbs / 29 kg average) Patients also saw 76% reduction in knee osteoarthritis pain Blood pressure reduced by 14 mmHg on average Source: ClinicalTrials.gov (TRIUMPH-4, NCT05931367) The TRIUMPH Phase 3 program includes 4 trials studying retatrutide for obesity, type 2 diabetes, and cardiovascular outcomes
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Remove the biggest triggers: eggs, cruciferous vegetables, garlic, onions, carbonated drinks, and sugar-free gum