10.1186/s13071-020-04119-w 22
Pre-clinical lung squamous cell carcinoma mouse models to identify novel biomarkers and therapeutic interventions
Why it matters: Rising use of GLP-1s is having a broader impact on multiple industries, including healthcare and pharma, apparel retailers, and consumer packaged goods
Additionally, nonhuman primate (NHP) models and animal models obtained from gut stem cell cultures are of great value to examine those hypotheses derived from clinical observations and for the formation of mechanistic and conceptual conclusions, which will accelerate their clinical translation and application
Its effects may vary by patient, dosage, formulation, and treatment plan
As a class, however, these agents work similarly where they mimic the structure of GLP-1 in vivo , and thus, can bind the GLP-1R, but are not subject to degradation by DPP-4