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181 Further, the activity of G6PD is also repressed by aspirin casing acetylation of G6PD to decrease the activity of G6PD and the generation of NADPH, and by RRx-001, a novel clinical-stage chemosensitizer and radiosensitizer, which exerts antiproliferative effects in human tumor cells

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This can be seen as a problem due to lack of standardization or as a feature that actually makes the findings more robust: whatever design flaws exist in one study are probably absent from the rest

S., Gelino, C., Stephens, D., Lunine, J

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They may act to induce general anesthesia, in which an unconscious state is achieved, or may act locally to induce numbness or lack of sensation at a targeted site