and payment or honoraria for presentation and travel/meeting support from the Obesity Medicine Association
Transdermal delivery eliminates the need for pills, though it introduces different considerations (adhesive sensitivity, consistent wear, etc.)
Adding GIP activity to GLP-1 activity changes the pharmacology in a way that is not just "more of the same." The full Zepbound titration goes 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg, 15mg, again four weeks at each step
Discontinuation Due to AEs: GLP-1 RAs were associated with an increased risk of treatment discontinuation due to AEs
In other words, the monthly cost depends on the prescribed strength, with maintenance doses such as 1.7mg or 2.4mg typically costing more but being more effective for long-term weight reduction
Adherence refers to the extent to which a patient follows prescribed therapeutic recommendations or instructions on the label, while persistence is the duration of time a patient continues to take a medication without discontinuing it