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A randomized phase II study of LY2510924 and carboplatin/etoposide versus carboplatin/etoposide in extensive-disease small cell lung cancer

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The redox cycling enzymes thioredoxin, thioredoxin reductase, sulfiredoxin, peroxiredoxin, GSH peroxidase, superoxide dismutase 1, and catalase, and several GSH S-transferases, which are the enzymes mediating the elimination of ROS, are all Nrf2 targets (242)

Supporting this idea, the GHK sequence occurs within the alpha-2 chain of type I collagen, which means proteolysis at a wound could in principle release free GHK locally

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Neuroprotection & Cognitive Function KPV: Reduces neuroinflammation, potentially benefiting conditions like Alzheimers and multiple sclerosis