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Compounding involves creating a medication specifically tailored to an individual's needs

IOC consensus statement on Relative Energy Deficiency in Sport (RED-S)

Quick Answer: Feeling cold on GLP-1 medications results from physiological changes during weight loss, including reduced insulating fat tissue, decreased caloric intake lowering heat production, and metabolic adaptations that make the body more energy-efficient

For instance, in the pivotal SURPASS-2 trial, patients receiving the highest tirzepatide dose (15 mg) achieved a mean body weight reduction of 11.2 kg, nearly twice that observed with semaglutide 1 mg (5.7 kg) (19)

Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications that mimic the action of a naturally occurring hormone in your body

As of now, there are no large-scale clinical trials specifically evaluating semaglutide for RA treatment