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Feature / Melanotan MT@ / PT-1414 Origin / MC1R, MC3R, MC4R / MC3R, MC4R Focus / Pigmentation + CNS / CNS signaling Selectivity / Broder / More Selective MT2 is often used in broader receptor studies, while PT-141 is studied for more targeted neurological effects

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At the fifteenth position, histidine is substituted with alanine

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